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Erick Carreira's Research Group
 
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Publications (present - 2005)

This is a complete list of recent (2005 - present) publications by E.M. Carreira.
For older publications (1988 - 2004) please refer to this site.

 

2014

254
J. Y. Hamilton, N. Hauser, D. Sarlah, E.M. Carreira, Angew. Chem. Int. Ed. 2014, 53, early view.
Iridium-Catalyzed Enantioselective Allyl–Allylsilane Cross-Coupling.
http://dx.doi.org/10.1002/anie.201406077
2014_hamilton_2


253
M. McLaughlin, R. Yazaki, T.C. Fessard, E.M. Carreira, Org. Lett. 2014, 16, asap.
Oxetanyl Peptides: Novel Peptidomimetic Modules for Medicinal Chemistry.
http://dx.doi.org/10.1021/ol501590n
2013_McLaughlin1
252 E.M. Carreira, T.C. Fessard, Chem. Rev. 2014, 114, asap.
Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities.
http://dx.doi.org/10.1021/cr500127b
2014_fessard_1
251 H.F. Zipfel, E.M. Carreira, Org. Lett. 2014, 16, 2854.
An Efficient Synthesis Strategy to the Core Structure of 6–5–6–5–6-Membered Epipolythiodiketopiperazines.
http://dx.doi.org/10.1021/ol500990f
2014_zipfel_1
250 S. Diethelm, F. Schoenebeck, E.M. Carreira, Org. Lett. 2014, 16, 960.
Mechanistic Insight into the Spirocyclopropane Isoxazolidine Ring Contraction.
http://dx.doi.org/10.1021/ol403693t
2014_diethelm_1
249 J. Egger, E.M. Carreira, Nat. Prod. Rep. 2014, 31, 449.
Efficient synthesis strategies by application of transition metal-catalyzed carbene/nitrene insertions into C–H bonds.
http://dx.doi.org/10.1039/C3NP70084D
2014_egger_1
248 S. Krautwald, M.A. Schafroth, D. Sarlah, E.M. Carreira, J. Am. Chem. Soc. 2014, 136, 3020.
Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis.
http://dx.doi.org/10.1021/ja5003247
2014_krautwald1
247 J.Y. Hamilton, D. Sarlah, E.M. Carreira, J. Am. Chem. Soc. 2014, 136, 3006.
Iridium-Catalyzed Enantioselective Allyl–Alkene Coupling.
http://dx.doi.org/10.1021/ja412962w
2014_hamilton_1
246 N. Armanino, M. Lafrance, E.M. Carreira, Org. Lett. 2014, 16, 572.
Autotandem Catalysis with Ruthenium: Remote Hydroesterification of Allylic Amides.
http://dx.doi.org/10.1021/ol4034463
2013_armanino_2
 

2013

245 A.R. Everitt, S. Clare, J.M. Perreira, G. Savidis, A.M. Aker, S.P. John, D. Sarlah, E.M. Carreira, S.J. Elledge, P. Kellam, A.L. Brass, Cell Reports 2013, 5, 895.
Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction.
http://dx.doi.org/10.1016/j.celrep.2013.10.033
2013_sarlah
244 A. Joliton, E.M. Carreira, Org. Lett. 2013, 15, 5147.
Ir-Catalyzed Preparation of SF5-Substituted Potassium Aryl Trifluoroborates via C–H Borylation and Their Application in the Suzuki–Miyaura Reaction.
http://dx.doi.org/10.1021/ol4025666
2013_joliton_1
243 O.F. Jeker, A.G. Kravina, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 12166.
Total Synthesis of (+)-Asperolide C by Iridium-Catalyzed Enantioselective Polyene Cyclization.
http://dx.doi.org/10.1002/anie.201307187
2013_jeker_1
242 S.A. Ruider, S. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 11908.
Ring Expansion of 3-Oxetanone-Derived Spirocycles: Facile Synthesis of Saturated Nitrogen Heterocycles.
http://dx.doi.org/10.1002/anie.201306563
2013_ruider1
241 D.B. Li, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2013, 15, 4766.
Construction of Multifunctional Modules for Drug Discovery: Synthesis of Novel Thia/Oxa-Azaspiro[3.4]octanes.
http://dx.doi.org/10.1021/ol402127b
2013_li_1
240 S. Breitler, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 11168. (VIP Paper)
Total Synthesis of (+)-Crotogoudin.
http://dx.doi.org/10.1002/anie.201305822
2013_breitler
239
J. A. Burkhard, G. Wuitschik, J.-M. Plancher, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2013, 15, 4312.
Synthesis and Stability of Oxetane Analogs of Thalidomide and Lenalidomide.
http://dx.doi.org/10.1021/ol401705a
2013_burkhard_1
238 J.Y. Hamilton, B. Morandi, E.M. Carreira, Synthesis 2013, 45, 1857.
Homologative Trifluoromethylation of Acetals.
http://dx.doi.org/10.1055/s-0033-1338485
2013_hamilton_3
237 S. Krautwald, D. Sarlah, M.A. Schafroth, E.M. Carreira, Science 2013, 340, 1065.
Enantio- and Diastereodivergent Dual Catalysis: α-Allylation of Branched Aldehydes.
http://dx.doi.org/10.1126/science.1237068
2013_krautwald_1
236 S. Diethelm, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 8500.
Total Synthesis of (±)-Gelsemoxonine.
http://dx.doi.org/10.1021/ja403823n
2013_diethelm_1
235 J.Y. Hamilton, D. Sarlah, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 7532.
Iridium-Catalyzed Enantioselective Allylic Alkynylation.
http://dx.doi.org/10.1002/anie.201302731
2013_hamilton_2
234 N. Armanino, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 6814.
Ruthenium-Catalyzed Intramolecular Hydrocarbamoylation of Allylic Formamides: Convenient Access to Chiral Pyrrolidones.
http://dx.doi.org/10.1021/ja4026787
2013_armanino_1
233 Q.A. Huchet, B. Kuhn, B. Wagner, H. Fischer, M. Kansy, D. Zimmerli, E.M. Carreira, K. Müller, J. Fluorine Chem. 2013, 152, 119.
On the polarity of partially fluorinated methyl groups.
http://dx.doi.org/10.1016/j.jfluchem.2013.02.023
2013_huchet_1
232 J. Egger, P. Bretscher, S. Freigang, M. Kopf, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 5382. (VIP Paper)
Synthesis of Epoxyisoprostanes: Effects in Reducing Secretion of Pro-inflammatory Cytokines IL-6 and IL-12.
http://dx.doi.org/10.1002/anie.201300739
2013_egger_1
231 L.M. Kreis, S. Krautwald, N. Pfeiffer, R.E. Martin, E.M. Carreira, Org. Lett. 2013, 15, 1634.
Photocatalytic Synthesis of Allylic Trifluoromethyl Substituted Styrene Derivatives in Batch and Flow.
http://dx.doi.org/10.1021/ol400410m
2013_kreis_1
230 J.Y. Hamilton, D. Sarlah, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 994.
Iridium-Catalyzed Enantioselective Allylic Vinylation.
http://dx.doi.org/10.1021/ja311422z
2013_hamilton1
 

2012

229 A.P. Frei, O-Y. Jeon, S. Kilcher, H. Moest, L.M. Henning, C. Jost, A. Plückthun, J. Mercer, R. Aebersold, E.M. Carreira, B. Wollscheid, Nature Biotechnology 2012, 30, 997.
Direct identification of ligand-receptor interactions on living cells and tissues.
http://dx.doi.org/10.1038/nbt.2354
2012_ock-youm
228 M.A. Schafroth, D. Sarlah, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc. 2012, 134, 20276.
Iridium-Catalyzed Enantioselective Polyene Cyclization.
http://dx.doi.org/10.1021/ja310386m
2012_schafroth
227 N. Huwyler, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 13066.
Total Synthesis and Stereochemical Revision of the Chlorinated Sesquiterpene (±)-Gomerone C.
http://dx.doi.org/10.1002/anie.201207203
2012_huwyler
226 C.M. Gampe, E.M. Carreira, Chem. Eur. J. 2012, 18, 15761.
Cyclohexyne Cycloinsertion in the Divergent Synthesis of Guanacastepenes.
http://dx.doi.org/10.1002/chem.201202222
2012_gampe_2
225 P. Zarotti, T.F. Knöpfel, P. Aschwanden, E.M. Carreira, ACS Catal. 2012, 2, 1232.
Nonlinear Effects with Diastereomeric Ligand Mixtures in Enantioselective, Catalytic Additions of Terminal Alkynes Involving Copper–PINAP Complexes.
http://dx.doi.org/10.1021/cs300146x
2012_zarotti
224 M.A. Ariger, E.M. Carreira, Org. Lett. 2012, 14, 4522.
pH-Independent Transfer Hydrogenation in Water: Catalytic, Enantioselective Reduction of β-Keto Esters.
http://dx.doi.org/10.1021/ol301903c
2012_ariger
223 M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 8652.
Enantioselective Allylic Thioetherification: The Effect of Phosphoric Acid Diester on Iridium-Catalyzed Enantioconvergent Transformations.
http://dx.doi.org/10.1002/anie.201202092
2012_roggen
222 F. Kleinbeck, G.J. Fettes, L.D. Fader, E.M. Carreira, Chem. Eur. J. 2012, 18, 3598.
Total Synthesis of Bafilomycin A1.
http://dx.doi.org/10.1002/chem.201102797
2008_kleinbeck
221 B. Morandi, A. Dolva, E.M. Carreira, Org. Lett. 2012, 14, 2162.
Iron-Catalyzed Cyclopropanation with Glycine Ethyl Ester Hydrochloride in Water.
http://dx.doi.org/10.1021/ol300688p
2012_morandi_3
220 S.A. Künzi, B. Morandi, E.M. Carreira, Org. Lett. 2012, 14, 1900.
Preparation of Trifluoromethyl-Substituted Aziridines with in Situ Generated CF3CHN2.
http://dx.doi.org/10.1021/ol300539e
2012_morandi_2
219 B. Morandi, E.M. Carreira, Science 2012, 335, 1471.
Iron-Catalyzed Cyclopropanation in 6 M KOH with in Situ Generation of Diazomethane.
http://dx.doi.org/10.1126/science.1218781
2012_morandi_1
218 C.M. Gampe, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3766.
Arynes and Cyclohexyne in Natural Product Synthesis.
http://dx.doi.org/10.1002/anie.201107485
2012_Gampe_1
217 C. Nilewski, E.M. Carreira, Eur. J. Org. Chem. 2012, 1685.
Recent Advances in the Total Synthesis of Chlorosulfolipids.
http://dx.doi.org/10.1002/ejoc.201101525
2012_nilewski_1
216 O.F. Jeker, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3474.
Total Synthesis and Stereochemical Reassignment of (±)-Indoxamycin B.
http://dx.doi.org/10.1002/anie.201109175
2012_jeker_1
215 L.M. Kreis, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3436.
Total Synthesis of (−)-Dendrobine.
http://dx.doi.org/10.1002/anie.201108564
2012_kreis_1
214 M. Lafrance, M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3470.
Direct, Enantioselective Iridium-Catalyzed Allylic Amination of Racemic Allylic Alcohols.
http://dx.doi.org/10.1002/anie.201108287
2012_lafrance_1
213 J.A. Burkhard, C. Guérot, H. Knust, E.M. Carreira, Org. Lett. 2012, 14, 66.
Expanding the Azaspiro[3.3]heptane Family: Synthesis of Novel Highly Functionalized Building Blocks.
http://dx.doi.org/10.1021/ol2028459
2011_burkhard_1
 

2011

212 B. Morandi, E.M. Carreira, Org. Lett. 2011, 13, 5984.
Expedient Preparation of Trifluoromethyl-Substituted Benzofuranols.
http://dx.doi.org/10.1021/ol202423s
2011_morandi_2
211
D.B. Li, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2011, 13, 6134.
Synthesis of Novel Azaspiro[3.4]octanes as Multifunctional Modules in Drug Discovery.
http://dx.doi.org/10.1021/ol2025313
2011_li_1
210 M.E. Weiss, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 11501. (VIP Paper)
Total Synthesis of (+)-Daphmanidin E.
http://dx.doi.org/10.1002/anie.201104681
2011_weiss_2
209 M.E. Weiss, L.M. Kreis, A. Lauber, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 11125.
Cobalt-Catalyzed Coupling of Alkyl Iodides with Alkenes: Deprotonation of Hydridocobalt Enables Turnover.
http://dx.doi.org/10.1002/anie.201105235
2011_weiss_1
208 A. Breder, G.M. Chinigo, A.W. Waltman, E.M. Carreira, Chem. Eur. J. 2011, 17, 12405.
Towards the Synthesis of Massadine: A Unified Strategy for the Stereoselective Synthesis of the Carbocyclic C,D-Ring Subunit.
http://dx.doi.org/10.1002/chem.201101862
2011_breder_1
207 T.J. Hoffman, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 10670.
Catalytic Asymmetric Intramolecular Hydroacylation with Rhodium/Phosphoramidite–Alkene Ligand Complexes.
http://dx.doi.org/10.1002/anie.201104595
2011_hoffman_1
206 W. Zhao, E.M. Carreira, Org. Lett. 2011, 13, 5048.
One-Pot Synthesis of Novel Photochromic Oxazine Compounds.
http://dx.doi.org/10.1021/ol2019482

2011_zhao_1
205 B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 9085.
Synthesis of Trifluoroethyl-Substituted Ketones from Aldehydes and Cyclohexanones.
http://dx.doi.org/10.1002/anie.201103526
2011_morandi_3
204 H. Vázquez-Villa, S. Reber, M.A. Ariger, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 8979.
Iridium Diamine Catalyst for the Asymmetric Transfer Hydrogenation of Ketones.
http://dx.doi.org/10.1002/anie.201102732

2011_vazquez
203
C. Nilewski, N.R. Deprez, T.C. Fessard, D.B. Li, R.W. Geisser, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 7940. (VIP paper)
Synthesis of Undecachlorosulfolipid A: Re-evaluation of the Nominal Structure.
http://dx.doi.org/10.1002/anie.201102521

2011_nilewski
202
B. Morandi, J. Cheang, E.M. Carreira, Org. Lett. 2011, 13, 3080.
Iron-Catalyzed Preparation of Trifluoromethyl Substituted Vinyl- and Alkynylcyclopropanes.
http://dx.doi.org/10.1021/ol200983s

2011_morandi
201
M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 5568.
Enantioselective Allylic Etherification: Selective Coupling of Two Unactivated Alcohols.
http://dx.doi.org/10.1002/anie.201007716

2011_roggen
200
J.A. Burkhard, B.H. Tchitchanov, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 5379. (hot paper)
Cascade Formation of Isoxazoles: Facile Base-Mediated Rearrangement of Substituted Oxetanes.
http://dx.doi.org/10.1002/anie.201100260

2011_burkhard
199
C.M. Gampe, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 2962.
Total Syntheses of Guanacastepenes N and O.
http://dx.doi.org/10.1002/anie.201007644

2011_gampe
198
N. Chinkov, A. Warm, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 2957.
Asymmetric Autocatalysis Enables an Improved Synthesis of Efavirenz.
http://dx.doi.org/10.1002/anie.201006689

2011_chinkov
197
M.P. Croatt, E.M. Carreira, Org. Lett. 2011, 13, 1390.
Probing the Role of the Mycosamine C2'-OH on the Activity of Amphotericin B.
http://dx.doi.org/10.1021/ol2000765

2011_croatt
196
C. Guérot, B.H. Tchitchanov, H. Knust, E.M. Carreira, Org. Lett. 2011, 13, 780.
Synthesis of Novel Angular Spirocyclic Azetidines.
http://dx.doi.org/10.1021/ol103050c

2011_guerot
195 B. Morandi, B. Mariampillai, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 1101.
Enantioselective Cobalt-Catalyzed Preparation of Trifluoromethyl-Substituted Cyclopropanes.
http://dx.doi.org/10.1002/anie.201004269

2010_morandi3
194 G.M. Chinigo, A. Breder, E.M. Carreira, Org. Lett. 2011, 13, 78.
Ugi-4-Component Reaction Enabling Rapid Access to the Core Fragment of Massadine.
http://dx.doi.org/10.1021/ol102577q

2010_chinigo
 

2010

193
A.M. Szpilman, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9592.
Probing the Biology of Natural Products: Molecular Editing by Diverted Total Synthesis.
http://dx.doi.org/10.1002/anie.200904761

2010_szpilman
192
J.A. Burkhard, G. Wuitschik, M. Rogers-Evans, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9052.
Oxetanes as Versatile Elements in Drug Discovery and Synthesis.
http://dx.doi.org/10.1002/anie.200907155

2010_burkhard3
191
C.S. Schindler, L. Bertschi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9229.
Total Synthesis of Nominal Banyaside B: Structural Revision of the Glycosylation Site.
http://dx.doi.org/10.1002/anie.201004047

2010_schindler_2
190
A.M. Szpilman, E.M. Carreira, "Cycloaddition Reactions", chapter 2 in "Silver in Organic Chemistry" (Ed. M. Harmata), John Wiley & Sons, Inc. (Hoboken, New Jersey), 2010.
http://onlinelibrary.wiley.com/doi/10.1002/9780470597521.ch2/summary
189
C.S. Schindler, P.M. Forster, E.M. Carreira, Org. Lett. 2010, 12, 4102.
Facile Formation of N-Acyl-oxazolidinone Derivatives Using Acid Fluorides.
http://dx.doi.org/10.1021/ol1016977

2010_schindler
188
S. Diethelm, C.S. Schindler, E.M. Carreira, Org. Lett. 2010, 12, 3950.
Synthesis of Microcin SF608 through Nucleophilic Opening of an Oxabicyclo[2.2.1]heptane.
http://dx.doi.org/10.1021/ol1017189

2010_diethelm
187
M. Roggen, E.M. Carreira, J. Am. Chem. Soc. 2010, 132, 11917.
Stereospecific Substitution of Allylic Alcohols To Give Optically Active Primary Allylic Amines: Unique Reactivity of a (P,alkene)Ir Complex Modulated by Iodide.
http://dx.doi.org/10.1021/ja105271z

2010_roggen
186
A.A. Volmer, A.M. Szpilman, E.M. Carreira, Nat. Prod. Rep. 2010, 27, 1329.
Synthesis and biological evaluation of amphotericin B derivatives.
http://dx.doi.org/10.1039/b820743g

2010_volmer_szpilman
185
O. Soltani, M.A. Ariger, H. Vázquez-Villa, E.M. Carreira, Org. Lett. 2010, 12, 2893.
Transfer Hydrogenation in Water: Enantioselective, Catalytic Reduction of α-Cyano and α-Nitro Substituted Acetophenones.
http://dx.doi.org/10.1021/ol1008894

2010_soltani
184
B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 4294.
Rhodium-Catalyzed Cyclopropenation of Alkynes: Synthesis of Trifluoromethyl-Substituted Cyclopropenes.
http://dx.doi.org/10.1002/anie.201000787

2010_morandi
183
C.M. Gampe, S. Boulos, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 4092.
Cyclohexyne Cycloinsertion by an Annulative Ring Expansion Cascade.
http://dx.doi.org/10.1002/anie.201001137

2010_gampe
182
J.A. Burkhard, B. Wagner, H. Fischer, F. Schuler, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 3524.
Synthesis of Azaspirocycles and their Evaluation in Drug Discovery.
http://dx.doi.org/10.1002/anie.200907108

2010_burkhard2
181
J.A. Burkhard, C. Guérot, H. Knust, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2010, 12, 1944.
Synthesis and Structural Analysis of a New Class of Azaspiro[3.3]heptanes as Building Blocks for Medicinal Chemistry.
http://dx.doi.org/10.1021/ol1003302

2010_burkhard
180
G. Wuitschik, E.M. Carreira, B. Wagner, H. Fischer, I. Parrilla, F. Schuler, M. Rogers-Evans, K. Müller, J. Med. Chem. 2010, 53, 3227.
Oxetanes in Drug Discovery: Structural and Synthetic Insights.
http://dx.doi.org/10.1021/jm9018788

2010_wuitschik
179
O.-Y. Jeon, E.M. Carreira, Org. Lett. 2010, 12, 1772.
Differential Interaction of an AmB Analogue and Ergosterol in Enantiomeric Membranes.
http://dx.doi.org/10.1021/ol1003516

2010_jeon
178
A.A. Volmer, E.M. Carreira, ChemBioChem 2010, 11, 778.
Active Amphotericin B Derivatives Position the Mycosamine in Two Radial Orientations.
http://dx.doi.org/10.1002/cbic.201000080

2010_volmer
177
B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 938.
Iron-Catalyzed Cyclopropanation with Trifluoroethylamine Hydrochloride and Olefins in Aqueous Media: In Situ Generation of Trifluoromethyl Diazomethane.
http://dx.doi.org/10.1002/anie.200905573

2009_morandi2
176
B. Gaspar, J. Waser, E.M. Carreira, Org. Syn. 2010, 87, 88.
Synthesis of (3-Chlorobutyl)benzene by the Cobalt-Catalyzed Hydrochlorination of 4-Phenyl-1-butene.
http://www.orgsyn.org/orgsyn/prep.asp?prep=v87p0088

2010_gaspar
 

2009

175
D. Muri, E.M. Carreira, J. Org. Chem. 2009, 74, 8695.
Stereoselective Synthesis of Erythronolide A via Nitrile Oxide Cycloadditions and Related Studies.
http://dx.doi.org/10.1021/jo901817b

2009_muri2
174
C. Nilewski, R.W. Geisser, M.-O. Ebert, E.M. Carreira, J. Am. Chem. Soc. 2009, 131, 15866.
Conformational and Configurational Analysis in the Study and Synthesis of Chlorinated Natural Products.
http://dx.doi.org/10.1021/ja906461h

2009_nilewski2
173
C.S. Schindler, E.M. Carreira, Chem. Soc. Rev. 2009, 38, 3222.
Rapid formation of complexity in the total synthesis of natural products enabled by oxabicyclo[2.2.1]heptene building blocks.
http://dx.doi.org/10.1039/b915448p

2009_schindler2
172 N. Lohse-Fraefel, E.M. Carreira, Chem. Eur. J. 2009, 15, 12065.
Polyketide Building Blocks via Diastereoselective Nitrile Oxide Cycloadditions with Homoallylic Alcohols and Monoprotected Homoallylic Diols.
http://dx.doi.org/10.1002/chem.200900529

2009_lohse
171
B. Gaspar, E.M. Carreira, J. Am. Chem. Soc. 2009, 131, 13214.
Cobalt Catalyzed Functionalization of Unactivated Alkenes: Regioselective Reductive C−C Bond Forming Reactions.
http://dx.doi.org/10.1021/ja904856k

2009_gaspar
170 O. Soltani, M.A. Ariger, E.M. Carreira, Org. Lett. 2009, 11, 4196.
Transfer Hydrogenation in Water: Enantioselective, Catalytic Reduction of (E)-β,β-Disubstituted Nitroalkenes.
http://dx.doi.org/10.1021/ol901332e

2009_soltani
169 C.S. Schindler, S. Diethelm, E.M. Carreira, Angew. Chem. Int. Ed. 2009, 48, 6296.
Nucleophilic Opening of Oxabicyclic Ring Systems.
http://dx.doi.org/10.1002/anie.200902046

2009_schindler
168
D. Muri, C. Corminboeuf, E.M. Carreira, D. Jeannerat, Magn. Reson. Chem. 2009, 47, 909.
Structure determination of slowly exchanging conformers in solution using high-resolution NMR, computational modeling and DFT-GIAO chemical shielding: application to an erythronolide A derivative.
http://dx.doi.org/10.1002/mrc.2476

2009_muri
167
B. Morandi, E.M. Carreira, Synlett 2009, 2076.
Catalytic Decarbonylation of Epoxyaldehydes: Applications to the Preparation of Terminal Epoxides.
http://dx.doi.org/10.1055/s-0029-1217562

2009_morandi
166
A.M. Szpilman, D.M. Cereghetti, J.M. Manthorpe, N.R. Wurtz, E.M. Carreira, Chem. Eur. J. 2009, 15, 7117.
Synthesis and Biophysical Studies on 35-Deoxy Amphotericin B Methyl Ester.
http://dx.doi.org/10.1002/chem.200900231

2009_szpilman2
165
A. Zumbuehl, P. Stano, M. Sohrmann, R. Dietiker, M. Peter, E.M. Carreira, ChemBioChem 2009, 10, 1617.
Synthesis and Investigation of Tryptophan-Amphotericin B Conjugates.
http://dx.doi.org/10.1002/cbic.200900096

2009_zumbuehl
164
A.M. Szpilman, E.M. Carreira, Org. Lett. 2009, 11, 1305.
β-Glycosidation of Sterically Hindered Alcohols.
http://dx.doi.org/10.1021/ol9000735

2009_szpilman
163 C. Nilewski, R.W. Geisser, E.M. Carreira, Nature 2009, 547, 573.
Total synthesis of a chlorosulpholipid cytotoxin associated with seafood poisoning.
http://dx.doi.org/10.1038/nature07734

2009_nilewski
162
E.M. Carreira and L. Kværnø, Classics in Stereoselective Synthesis, Wiley: Weinheim, 2009.

2009_classics
161
F. Kleinbeck, E.M. Carreira, Angew. Chem. Int. Ed. 2009, 48, 578.
Total Synthesis of Bafilomycin A1.
http://dx.doi.org/10.1002/anie.200804645

2008_kleinbeck
 

2008

160
C.S. Schindler, C.R.J. Stephenson, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 8852.
Enantioselective Synthesis of the Core of Banyaside, Suomilide, and Spumigin HKVV.
http://dx.doi.org/10.1002/anie.200803655

2008_schindler
159
A. Breder, G.M. Chinigo, A.W. Waltman, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 8514.
Enantioselective Synthesis of the Carbocyclic D-Ring Subunit of Massadine.
http://dx.doi.org/10.1002/anie.200803284

2008_breder
158
K.-H. Altmann, E.M. Carreira, Nat. Chem. Biol. 2008, 4, 388.
Unraveling a molecular target of macrolides.
http://dx.doi.org/10.1038/nchembio0708-388
157
J. Burkhard, E.M. Carreira, Org. Lett. 2008, 10, 3525.
2,6-Diazaspiro[3.3]heptanes: Synthesis and Application in Pd-Catalyzed Aryl Amination Reactions.
http://dx.doi.org/10.1021/ol801293f

2008_burkhard
156
B. Gaspar, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 5758.
Catalytic Hydrochlorination of Unactivated Olefins with para-Toluenesulfonyl Chloride.
http://dx.doi.org/10.1002/ange.200801760

2008_gaspar
155
G. Wuitschik, M. Rogers-Evans, A. Buckl, M. Bernasconi, M. Märki, T. Godel, H. Fischer, B. Wagner, I. Parrilla, F. Schuler, J. Schneider, A. Alker, W.B. Schweizer, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4512.
Spirocyclic Oxetanes: Synthesis and Properties.
http://dx.doi.org/10.1002/anie.200800450

2008_wuitschik
154 A.M. Szpilman, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4339.
Synthesis and Biological Studies of 35-Deoxy-Amphotericin B Methyl Ester.
http://dx.doi.org/10.1002/anie.200800590

2008_szpilman_02
153 A.M. Szpilman, D.M. Cereghetti, N.R. Wurtz, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4335.
Synthesis of 35-Deoxy Amphotericin B Methylester: A Strategy for Molecular Editing.
http://dx.doi.org/10.1002/anie.200800589

2008_szpilman_01
152
J. Waser, E.M. Carreira, Azides by Olefin Hydroazidation Reactions (book chapter), in press.
151
C. Defieber, E.M. Carreira, Modern Arylation Methods, L. Ackerman Ed.
Modern Arylation of Carbonyl Compounds.
150
C. Defieber, H. Grützmacher, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4482.
Chiral Olefins as Steering Ligands in Asymmetric Catalysis.
http://dx.doi.org/10.1002/anie.200703612

2008_defieber
149
V. Paquet, A.A. Volmer, E.M. Carreira, Chem. Eur. J. 2008, 14, 2465.
Synthesis and In Vitro Biological Properties of Novel Cationic Derivatives of Amphotericin B.
http://dx.doi.org/10.1002/chem.200701237

2008_paquet
 

2007

148
B. Gaspar, J. Waser, E.M. Carreira, Synthesis 2007, 3839.
Cobalt-Catalyzed Synthesis of Tertiary Azides from α,α-Disubstituted Olefins under Mild Conditions Using Commercially Available Reagents.
http://dx.doi.org/10.1055/s-2007-1000817

2007_gaspar2
147
T.C. Fessard, S.P. Andrews, H. Motoyoshi, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 9331.
Enantioselective Preparation of 1,1-Diarylethanes: Aldehydes as Removable Steering Groups for Asymmetric Synthesis.
http://dx.doi.org/10.1002/anie.200702995

2007_fessard2
146 N. Becker, E.M. Carreira, Org. Lett. 2007, 9, 3857.
Hydroxyl-directed nitrile oxide cycloaddition reactions with cyclic allylic alcohols.
http://dx.doi.org/10.1021/ol7017032

2007_becker2
145
S. Fujimori, E.M. Carreira, Bull. Chem. Soc. Jpn. 2007, 80, 1635.
Stereoselective Conjugate Addition Reactions Using In Situ Metallated Terminal Alkynes and the Development of Novel Chiral P,N-Ligands.
http://dx.doi.org/10.1246/bcsj.80.1635

2007_fujimori3
144
S. Fujimori, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 4967.
Cu(I)-catalyzed conjugate addition of ethyl propiolate.
http://dx.doi.org/10.1002/anie.200701098

2007_fujimori2

143

C. Czekelius, E.M. Carreira, Org. Process Res. Dev. 2007, 11, 633.
Enantioselective reduction of nitroalkene mixtures by in situ equilibration.
http://dx.doi.org/10.1021/op700029m

2007_czekelius
142
M. Knöpfel, J.P. Davies, P.T. Duong, L. Kværnø, E.M. Carreira, M.C. Phillips, Y.A. Ioannou, H. Hauser, Biochim. Biophys. Acta 2007, 1771, 1140.
Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.
http://dx.doi.org/10.1016/j.bbalip.2007.05.011

2007_knoepfel

141

B. Gaspar, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 4519.
Mild Cobalt-Catalyzed Hydrocyanation of Olefins with Tosyl Cyanide.
http://dx.doi.org/10.1002/anie.200700575

2007_gaspar

140

C. Defieber, M.A. Ariger, P. Moriel, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 3139.
Iridium-catalyzed synthesis of primary allylic amines from allylic alcohols: Sulfamic acid as ammonia equivalent.
http://dx.doi.org/10.1002/anie.200700159

2007_defieber

139

T.C. Fessard, H. Motoyoshi, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 2078.
Pd-catalyzed cleavage of benzylic nitro bonds: New opportunities for asymmetric synthesis.
http://dx.doi.org/10.1002/anie.200604263

2007_fessard
138
W.L. Zhao, E.M. Carreira, Chem. Eur. J. 2007, 13, 2671.
Oligothiophene-linked bisnaphthopyrans: Sequential and temperature-dependent photochromism.
http://dx.doi.org/10.1002/chem.200600958

2007_zhao

137

A. Zumbuehl, P. Stano, M. Sohrmann, M. Peter, P. Walde, E.M. Carreira, Org. Biomol. Chem. 2007, 5, 1339.
A novel strategy for bioconjugation: synthesis and preliminary evaluation with amphotericin B.
http://dx.doi.org/10.1039/b701953j

2007_zumbuehl
 

2006

136
V. Paquet, A. Zumbuehl, E.M. Carreira, Bioconjugate Chem. 2006, 17, 1460.
Biologically active amphotericin B-calix[4] arene conjugates.
http://dx.doi.org/10.1021/bc060205i

2006_paquet
135
I. Lyothier, C. Defieber, E.M. Carreira, Angew. Chem. Int. Ed. 2006, 45, 6204.
Iridium-catalyzed enantioselective synthesis of allylic alcohols: Silanolates as hydroxide equivalents.
http://dx.doi.org/10.1002/anie.200602408

2006_lyothier
134
G. Wuitschik, M. Rogers-Evans, K. Muller, H. Fischer, B. Wagner, F. Schuler, L. Polonchuk, E.M. Carreira, Angew. Chem. Int. Ed. 2006, 45, 7736.
Oxetanes as promising modules in drug discovery.
http://dx.doi.org/10.1002/anie.200602343

2006_wuitschik
133
P. Aschwanden, C.R.J. Stephenson, E.M. Carreira, Org. Lett. 2006, 8, 2437.
Highly enantioselective access to primary propargylamines: 4-piperidinone as a convenient protecting group.
http://dx.doi.org/10.1021/ol060876w

2006_aschwanden
132 J. Waser, B. Gaspar, H. Nambu, E.M. Carreira, J. Am. Chem. Soc. 2006, 128, 11693.
Hydrazines and azides via the metal-catalyzed hydrohydrazination and hydroazidation of olefins.
http://dx.doi.org/10.1021/ja062355+

2006_waser
131
D.M. Cereghetti, E.M. Carreira, Synthesis 2006, 914.
Amphotericin B: 50 years of chemistry and biochemistry.
http://dx.doi.org/10.1055/s-2006-926368

2006_cereghetti
130
V. Paquet, E.M. Carreira, Org. Lett. 2006, 8, 1807.
Significant improvement of antifungal activity of polyene macrolides by bisalkylation of the mycosamine.
http://dx.doi.org/10.1021/ol060353o

2006_paquet_ol
129
W. Zhao, E.M. Carreira, Org. Lett. 2006, 8, 99.
Synthesis and Photochromism of Novel Phenylene-Linked Photochromic Bispyrans.
http://dx.doi.org/10.1021/ol052587y

2006_zhao_ol

128

A. Lerchner, E.M. Carreira, Chem. Eur. J. 2006, 12, 8209.
Synthesis of (+/-)-strychnofoline via a highly convergent selective annulation reaction.
http://dx.doi.org/10.1002/chem.200600957

2006_lerchner

127

W.L. Zhao, E.M. Carreira, Chem. Eur. J. 2006, 12, 7254.
Conformationally restricted Aza-BODIPY: Highly fluorescent, stable near-infrared absorbing dyes.
http://dx.doi.org/10.1002/chem.200600527

2006_zhao
 

2005

126
P. Aschwanden, L. Kværnø, R.W. Geisser, F. Kleinbeck, E.M. Carreira, Org. Lett. 2005, 25, 5741.
Reduction of 2,3-Dihydroisoxazoles to beta-Amino Ketones and beta-Amino Alcohols.
http://dx.doi.org/10.1021/ol052540c

2005_aschwanden
125
J.M. Manthorpe, A.M. Szpilman, E.M. Carreira, Synthesis 2005, 3380.
Scalable Synthesis of a Mycosamine donor. Overcoming Difficult Reactivity in Allose Systems.
http://dx.doi.org/10.1055/s-2005-918474

2005_manthorpe
124 D. Topić, P. Aschwanden, R. Fässler, E.M. Carreira, Org. Lett. 2005, 7, 5329.
ZnCl2-Mediated Stereoselective Addition of Terminal Alkynes to D-(+)-Mannofuranosyl Nitrones.
http://dx.doi.org/10.1021/ol052331s


2005_topic
123 J. Waser, J.C. González-Gómez, H. Nambu, P. Huber, E.M. Carreira, Org. Lett. 2005, 7, 4249.
Cobalt-catalyzed hydrohydrazination of dienes and enynes: Access to allylic and propargylic hydrazides.
http://dx.doi.org/10.1021/ol0517473

2005_waser
122
T. Ritter, L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, Org. Biomol. Chem. 2005, 19, 3514.
Heterocyclic Ring Scaffolds as Small-Molecule Cholesterol Absorption Inhibitors.
http://dx.doi.org/10.1039/b510100j

2005_ritter
121
J.-F. Paquin, C.R.J. Stephenson, C. Defieber, E.M. Carreira, Org. Lett. 2005, 7, 3821.
Catalytic Asymmetric Synthesis with Rh-Diene Complexes: 1,4-Addition of Arylboronic Acids to Unsaturated Esters.
http://dx.doi.org/10.1021/ol051533l

2005_paquin
120
J.-F. Paquin, C. Defieber, C.R.J. Stephenson, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 10850.
Asymmetric Synthesis of 3,3-Diarylpropanals with Chiral Diene-Rhodium Catalysts.
http://dx.doi.org/10.1021/ja053270w

2005_paquin2
119
T. Knöpfel, P. Zarotti, Y. Takashi, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 9682.
Catalytic, Enantioselective, Conjugate Alkyne Addition.
http://dx.doi.org/10.1021/ja052411r

2005_knoepfel
118
J. Waser, H. Nambu, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 8294.
Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides.
http://dx.doi.org/10.1021/ja052164r

2005_waser2
117
L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, J. Med. Chem. 2005, 48, 6035.
Synthesis and In Vitro Evaluation of Inhibitors of Intestinal Cholesterol Absorption.
http://dx.doi.org/10.1021/jm050422p

2005_kvaerno
116
C. Marti, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 11505.
Total Synthesis of (-)-Spirotryprostatin B - Synthesis and Related Studies.
http://dx.doi.org/10.1021/ja0518880

2005_marti
115
N. Lohse-Fraefel, E.M. Carreira, Org. Lett. 2005, 7, 2011.
A Modular Approach to Polyketide Building Blocks: Cycloadditions of Nitrile Oxides and Homoallylic Alcohols.
http://dx.doi.org/10.1021/ol0504953

2005_lohse
114
W. Zhao, E.M. Carreira, Org. Lett. 2005, 7, 1609.
Solid Phase Synthesis of Photochromic Spiropyrans.
http://dx.doi.org/10.1021/ol050302b

2005_zhao
113
L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, Org. Lett. 2005, 7, 1145.
Carbohydrate Sulfonyl Chlorides for the Simple, Convenient Access to Glycoconjugates.
http://dx.doi.org/10.1021/ol0502127

2005_kvaerno2
112
D. Muri, N. Lohse, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 4036.
Total Synthesis of Erythronolide A via Mg(II)-Mediated Nitrile Oxide Cycloaddition.
http://dx.doi.org/10.1002/anie.200500172

2005_muri
111
C. Czekelius, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 612.
Convenient Transformation of Optically Active Nitroalkanes into Chiral Aldoximes and Nitriles.
http://dx.doi.org/10.1002/anie.200461879

2005_czekelius
110
W. Zhao, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 1677.
Conformationally Restricted Aza-BODIPY:  A Highly Fluorescent, Stable Near-Infrared Absorbing Dye.
http://dx.doi.org/10.1002/anie.200461868

2005_zhao2
 

2004 - 1988

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