Publications 2005-2013

Main content

2012   2011  2010  2009  2008   2007   2006   2005     

2013

245

Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction.

A.R. Everitt, S. Clare, J.M. Perreira, G. Savidis, A.M. Aker, S.P. John, D. Sarlah, E.M. Carreira, S.J. Elledge, P. Kellam, A.L. Brass, Cell Reports 2013, 5, 895.
http://dx.doi.org/10.1016/j.celrep.2013.10.033

244

Ir-Catalyzed Preparation of SF5-Substituted Potassium Aryl Trifluoroborates via C–H Borylation and Their Application in the Suzuki–Miyaura Reaction.

A. Joliton, E.M. Carreira, Org. Lett. 2013, 15, 5147.
http://dx.doi.org/10.1021/ol4025666

243

Total Synthesis of (+)-Asperolide C by Iridium-Catalyzed Enantioselective Polyene Cyclization.

O.F. Jeker, A.G. Kravina, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 12166.
http://dx.doi.org/10.1002/anie.201307187

242

Ring Expansion of 3-Oxetanone-Derived Spirocycles: Facile Synthesis of Saturated Nitrogen Heterocycles.

S.A. Ruider, S. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 11908.
http://dx.doi.org/10.1002/anie.201306563

241

Construction of Multifunctional Modules for Drug Discovery: Synthesis of Novel Thia/Oxa-Azaspiro[3.4]octanes.

D.B. Li, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2013, 15, 4766.
http://dx.doi.org/10.1021/ol402127b

240

Total Synthesis of (+)-Crotogoudin.

S. Breitler, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 11168. (VIP Paper)
http://dx.doi.org/10.1002/anie.201305822

239

Synthesis and Stability of Oxetane Analogs of Thalidomide and Lenalidomide.

J. A. Burkhard, G. Wuitschik, J.-M. Plancher, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2013, 15, 4312.
http://dx.doi.org/10.1021/ol401705a

238

Homologative Trifluoromethylation of Acetals.

J.Y. Hamilton, B. Morandi, E.M. Carreira, Synthesis 2013, 45, 1857.
http://dx.doi.org/10.1055/s-0033-1338485

237

Enantio- and Diastereodivergent Dual Catalysis: α-Allylation of Branched Aldehydes.

S. Krautwald, D. Sarlah, M.A. Schafroth, E.M. Carreira, Science 2013, 340, 1065.
http://dx.doi.org/10.1126/science.1237068

236

Total Synthesis of (±)-Gelsemoxonine.

S. Diethelm, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 8500.
http://dx.doi.org/10.1021/ja403823n

235

Iridium-Catalyzed Enantioselective Allylic Alkynylation.

J.Y. Hamilton, D. Sarlah, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 7532.
http://dx.doi.org/10.1002/anie.201302731

234

Ruthenium-Catalyzed Intramolecular Hydrocarbamoylation of Allylic Formamides: Convenient Access to Chiral Pyrrolidones.

N. Armanino, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 6814.
http://dx.doi.org/10.1021/ja4026787

233

On the Polarity of Partially Fluorinated Methyl Groups.

Q.A. Huchet, B. Kuhn, B. Wagner, H. Fischer, M. Kansy, D. Zimmerli, E.M. Carreira, K. Müller, J. Fluorine Chem. 2013, 152, 119.
http://dx.doi.org/10.1016/j.jfluchem.2013.02.023

232

Synthesis of Epoxyisoprostanes: Effects in Reducing Secretion of Pro-inflammatory Cytokines IL-6 and IL-12.

J. Egger, P. Bretscher, S. Freigang, M. Kopf, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 5382. (VIP Paper)
http://dx.doi.org/10.1002/anie.201300739

231

Photocatalytic Synthesis of Allylic Trifluoromethyl Substituted Styrene Derivatives in Batch and Flow.

L.M. Kreis, S. Krautwald, N. Pfeiffer, R.E. Martin, E.M. Carreira, Org. Lett. 2013, 15, 1634.
http://dx.doi.org/10.1021/ol400410m

230

Iridium-Catalyzed Enantioselective Allylic Vinylation.

J.Y. Hamilton, D. Sarlah, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 994.
http://dx.doi.org/10.1021/ja311422z    

2012

229

Direct Identification of Ligand-Receptor Interactions on Living Cells and Tissues.

A.P. Frei, O-Y. Jeon, S. Kilcher, H. Moest, L.M. Henning, C. Jost, A. Plückthun, J. Mercer, R. Aebersold, E.M. Carreira, B. Wollscheid, Nature Biotechnology 2012, 30, 997.
http://dx.doi.org/10.1038/nbt.2354

228

Iridium-Catalyzed Enantioselective Polyene Cyclization.

M.A. Schafroth, D. Sarlah, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc. 2012, 134, 20276.
http://dx.doi.org/10.1021/ja310386m

227

Total Synthesis and Stereochemical Revision of the Chlorinated Sesquiterpene (±)-Gomerone C.

N. Huwyler, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 13066.
http://dx.doi.org/10.1002/anie.201207203

226

Cyclohexyne Cycloinsertion in the Divergent Synthesis of Guanacastepenes.

C.M. Gampe, E.M. Carreira, Chem. Eur. J. 2012, 18, 15761.
http://dx.doi.org/10.1002/chem.201202222

225

Nonlinear Effects with Diastereomeric Ligand Mixtures in Enantioselective, Catalytic Additions of Terminal Alkynes Involving Copper–PINAP Complexes.

P. Zarotti, T.F. Knöpfel, P. Aschwanden, E.M. Carreira, ACS Catal. 2012, 2, 1232.
http://dx.doi.org/10.1021/cs300146x

224

pH-Independent Transfer Hydrogenation in Water: Catalytic, Enantioselective Reduction of β-Keto Esters.

M.A. Ariger, E.M. Carreira, Org. Lett. 2012, 14, 4522.
http://dx.doi.org/10.1021/ol301903c

223

Enantioselective Allylic Thioetherification: The Effect of Phosphoric Acid Diester on Iridium-Catalyzed Enantioconvergent Transformations.

M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 8652.
http://dx.doi.org/10.1002/anie.201202092

222

Total Synthesis of Bafilomycin A1.

F. Kleinbeck, G.J. Fettes, L.D. Fader, E.M. Carreira, Chem. Eur. J. 2012, 18, 3598.
http://dx.doi.org/10.1002/chem.201102797

221

Iron-Catalyzed Cyclopropanation with Glycine Ethyl Ester Hydrochloride in Water.

B. Morandi, A. Dolva, E.M. Carreira, Org. Lett. 2012, 14, 2162.
http://dx.doi.org/10.1021/ol300688p

220

Preparation of Trifluoromethyl-Substituted Aziridines with in Situ Generated CF3CHN2.

S.A. Künzi, B. Morandi, E.M. Carreira, Org. Lett. 2012, 14, 1900.
http://dx.doi.org/10.1021/ol300539e

219

Iron-Catalyzed Cyclopropanation in 6 M KOH with in Situ Generation of Diazomethane.

B. Morandi, E.M. Carreira, Science 2012, 335, 1471.
http://dx.doi.org/10.1126/science.1218781

218

Arynes and Cyclohexyne in Natural Product Synthesis.

C.M. Gampe, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3766.
http://dx.doi.org/10.1002/anie.201107485

217

Recent Advances in the Total Synthesis of Chlorosulfolipids.

C. Nilewski, E.M. Carreira, Eur. J. Org. Chem. 2012, 1685.
http://dx.doi.org/10.1002/ejoc.201101525

216

Total Synthesis and Stereochemical Reassignment of (±)-Indoxamycin B.

O.F. Jeker, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3474.
http://dx.doi.org/10.1002/anie.201109175

215

Total Synthesis of (−)-Dendrobine.

L.M. Kreis, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3436.
http://dx.doi.org/10.1002/anie.201108564

214

Direct, Enantioselective Iridium-Catalyzed Allylic Amination of Racemic Allylic Alcohols.

M. Lafrance, M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3470.
http://dx.doi.org/10.1002/anie.201108287

213

Expanding the Azaspiro[3.3]heptane Family: Synthesis of Novel Highly Functionalized Building Blocks.

J.A. Burkhard, C. Guérot, H. Knust, E.M. Carreira, Org. Lett. 2012, 14, 66.
http://dx.doi.org/10.1021/ol2028459    

2011

212

Expedient Preparation of Trifluoromethyl-Substituted Benzofuranols.

B. Morandi, E.M. Carreira, Org. Lett. 2011, 13, 5984.
http://dx.doi.org/10.1021/ol202423s

211

Synthesis of Novel Azaspiro[3.4]octanes as Multifunctional Modules in Drug Discovery.

D.B. Li, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2011, 13, 6134.
http://dx.doi.org/10.1021/ol2025313

210

Total Synthesis of (+)-Daphmanidin E.

M.E. Weiss, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 11501. (VIP Paper)
http://dx.doi.org/10.1002/anie.201104681

209

Cobalt-Catalyzed Coupling of Alkyl Iodides with Alkenes: Deprotonation of Hydridocobalt Enables Turnover.

M.E. Weiss, L.M. Kreis, A. Lauber, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 11125.
http://dx.doi.org/10.1002/anie.201105235

208

Towards the Synthesis of Massadine: A Unified Strategy for the Stereoselective Synthesis of the Carbocyclic C,D-Ring Subunit.

A. Breder, G.M. Chinigo, A.W. Waltman, E.M. Carreira, Chem. Eur. J. 2011, 17, 12405.
http://dx.doi.org/10.1002/chem.201101862

207

Catalytic Asymmetric Intramolecular Hydroacylation with Rhodium/Phosphoramidite–Alkene Ligand Complexes.

T.J. Hoffman, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 10670.
http://dx.doi.org/10.1002/anie.201104595

206

One-Pot Synthesis of Novel Photochromic Oxazine Compounds.

W. Zhao, E.M. Carreira, Org. Lett. 2011, 13, 5048.
http://dx.doi.org/10.1021/ol2019482

205

Synthesis of Trifluoroethyl-Substituted Ketones from Aldehydes and Cyclohexanones

B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 9085.
http://dx.doi.org/10.1002/anie.201103526

204

Iridium Diamine Catalyst for the Asymmetric Transfer Hydrogenation of Ketones.

H. Vázquez-Villa, S. Reber, M.A. Ariger, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 8979.
http://dx.doi.org/10.1002/anie.201102732

203

Synthesis of Undecachlorosulfolipid A: Re-evaluation of the Nominal Structure.

C. Nilewski, N.R. Deprez, T.C. Fessard, D.B. Li, R.W. Geisser, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 7940. (VIP paper)
http://dx.doi.org/10.1002/anie.201102521

202

Iron-Catalyzed Preparation of Trifluoromethyl Substituted Vinyl- and Alkynylcyclopropanes.

B. Morandi, J. Cheang, E.M. Carreira, Org. Lett. 2011, 13, 3080.
http://dx.doi.org/10.1021/ol200983s

201

Enantioselective Allylic Etherification: Selective Coupling of Two Unactivated Alcohols.

M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 5568.
http://dx.doi.org/10.1002/anie.201007716

200

Cascade Formation of Isoxazoles: Facile Base-Mediated Rearrangement of Substituted Oxetanes.

J.A. Burkhard, B.H. Tchitchanov, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 5379. (hot paper)
http://dx.doi.org/10.1002/anie.201100260

199

Total Syntheses of Guanacastepenes N and O.

C.M. Gampe, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 2962.
http://dx.doi.org/10.1002/anie.201007644

198

Asymmetric Autocatalysis Enables an Improved Synthesis of Efavirenz.

N. Chinkov, A. Warm, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 2957.
http://dx.doi.org/10.1002/anie.201006689

197

Probing the Role of the Mycosamine C2'-OH on the Activity of Amphotericin B.

M.P. Croatt, E.M. Carreira, Org. Lett. 2011, 13, 1390.
http://dx.doi.org/10.1021/ol2000765

196

Synthesis of Novel Angular Spirocyclic Azetidines.

C. Guérot, B.H. Tchitchanov, H. Knust, E.M. Carreira, Org. Lett. 2011, 13, 780.
http://dx.doi.org/10.1021/ol103050c

195

Enantioselective Cobalt-Catalyzed Preparation of Trifluoromethyl-Substituted Cyclopropanes.

B. Morandi, B. Mariampillai, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 1101.
http://dx.doi.org/10.1002/anie.201004269

194

Ugi-4-Component Reaction Enabling Rapid Access to the Core Fragment of Massadine.

G.M. Chinigo, A. Breder, E.M. Carreira, Org. Lett. 2011, 13, 78.
http://dx.doi.org/10.1021/ol102577q    

2010

193

Probing the Biology of Natural Products: Molecular Editing by Diverted Total Synthesis.

A.M. Szpilman, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9592.
http://dx.doi.org/10.1002/anie.200904761

192

Oxetanes as Versatile Elements in Drug Discovery and Synthesis.

J.A. Burkhard, G. Wuitschik, M. Rogers-Evans, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9052.
http://dx.doi.org/10.1002/anie.200907155

191

Total Synthesis of Nominal Banyaside B: Structural Revision of the Glycosylation Site.

C.S. Schindler, L. Bertschi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9229.
http://dx.doi.org/10.1002/anie.201004047

190

A.M. Szpilman, E.M. Carreira, "Cycloaddition Reactions", chapter 2 in "Silver in Organic Chemistry" (Ed. M. Harmata), John Wiley & Sons, Inc. (Hoboken, New Jersey), 2010.
http://onlinelibrary.wiley.com/doi/10.1002/9780470597521.ch2/summar

189

Facile Formation of N-Acyl-oxazolidinone Derivatives Using Acid Fluorides.

C.S. Schindler, P.M. Forster, E.M. Carreira, Org. Lett. 2010, 12, 4102.
http://dx.doi.org/10.1021/ol1016977

188

Synthesis of Microcin SF608 through Nucleophilic Opening of an Oxabicyclo[2.2.1]heptane.

S. Diethelm, C.S. Schindler, E.M. Carreira, Org. Lett. 2010, 12, 3950.
http://dx.doi.org/10.1021/ol1017189

187

Stereospecific Substitution of Allylic Alcohols To Give Optically Active Primary Allylic Amines: Unique Reactivity of a (P,alkene)Ir Complex Modulated by Iodide.

M. Roggen, E.M. Carreira, J. Am. Chem. Soc. 2010, 132, 11917.
http://dx.doi.org/10.1021/ja105271z

186

Synthesis and Biological Evaluation of Amphotericin B Derivatives.

A.A. Volmer, A.M. Szpilman, E.M. Carreira, Nat. Prod. Rep. 2010, 27, 1329.
http://dx.doi.org/10.1039/b820743g

185

Transfer Hydrogenation in Water: Enantioselective, Catalytic Reduction of α-Cyano and α-Nitro Substituted Acetophenones.

O. Soltani, M.A. Ariger, H. Vázquez-Villa, E.M. Carreira, Org. Lett. 2010, 12, 2893.
http://dx.doi.org/10.1021/ol1008894

184

Rhodium-Catalyzed Cyclopropenation of Alkynes: Synthesis of Trifluoromethyl-Substituted Cyclopropenes.

B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 4294.
http://dx.doi.org/10.1002/anie.201000787

183

Cyclohexyne Cycloinsertion by an Annulative Ring Expansion Cascade.

C.M. Gampe, S. Boulos, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 4092.
http://dx.doi.org/10.1002/anie.201001137

182

Synthesis of Azaspirocycles and their Evaluation in Drug Discovery.

J.A. Burkhard, B. Wagner, H. Fischer, F. Schuler, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 3524.
http://dx.doi.org/10.1002/anie.200907108

181

Synthesis and Structural Analysis of a New Class of Azaspiro[3.3]heptanes as Building Blocks for Medicinal Chemistry.

J.A. Burkhard, C. Guérot, H. Knust, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2010, 12, 1944.
http://dx.doi.org/10.1021/ol1003302

180

Oxetanes in Drug Discovery: Structural and Synthetic Insights.

G. Wuitschik, E.M. Carreira, B. Wagner, H. Fischer, I. Parrilla, F. Schuler, M. Rogers-Evans, K. Müller, J. Med. Chem. 2010, 53, 3227.
http://dx.doi.org/10.1021/jm9018788

179

Differential Interaction of an AmB Analogue and Ergosterol in Enantiomeric Membranes.

O.-Y. Jeon, E.M. Carreira, Org. Lett. 2010, 12, 1772.
http://dx.doi.org/10.1021/ol1003516

178

Active Amphotericin B Derivatives Position the Mycosamine in Two Radial Orientations.

A.A. Volmer, E.M. Carreira, ChemBioChem 2010, 11, 778.
http://dx.doi.org/10.1002/cbic.201000080

177

Iron-Catalyzed Cyclopropanation with Trifluoroethylamine Hydrochloride and Olefins in Aqueous Media: In Situ Generation of Trifluoromethyl Diazomethane.

B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 938.
http://dx.doi.org/10.1002/anie.200905573

176

Synthesis of (3-Chlorobutyl)benzene by the Cobalt-Catalyzed Hydrochlorination of 4-Phenyl-1-butene.

B. Gaspar, J. Waser, E.M. Carreira, Org. Syn. 2010, 87, 88.
http://www.orgsyn.org/orgsyn/prep.asp?prep=v87p0088

2009

175

Stereoselective Synthesis of Erythronolide A via Nitrile Oxide Cycloadditions and Related Studies.

D. Muri, E.M. Carreira, J. Org. Chem. 2009, 74, 8695.
http://dx.doi.org/10.1021/jo901817b

174

Conformational and Configurational Analysis in the Study and Synthesis of Chlorinated Natural Products.

C. Nilewski, R.W. Geisser, M.-O. Ebert, E.M. Carreira, J. Am. Chem. Soc. 2009, 131, 15866.
http://dx.doi.org/10.1021/ja906461h

173

Rapid formation of complexity in the total synthesis of natural products enabled by oxabicyclo[2.2.1]heptene building blocks.

C.S. Schindler, E.M. Carreira, Chem. Soc. Rev. 2009, 38, 3222.
http://dx.doi.org/10.1039/b915448p

172

Polyketide Building Blocks via Diastereoselective Nitrile Oxide Cycloadditions with Homoallylic Alcohols and Monoprotected Homoallylic Diols.

N. Lohse-Fraefel, E.M. Carreira, Chem. Eur. J. 2009, 15, 12065.
http://dx.doi.org/10.1002/chem.200900529

171

Cobalt Catalyzed Functionalization of Unactivated Alkenes: Regioselective Reductive C−C Bond Forming Reactions.

B. Gaspar, E.M. Carreira, J. Am. Chem. Soc. 2009, 131, 13214.
http://dx.doi.org/10.1021/ja904856k

170

Transfer Hydrogenation in Water: Enantioselective, Catalytic Reduction of (E)-β,β-Disubstituted Nitroalkenes.

O. Soltani, M.A. Ariger, E.M. Carreira, Org. Lett. 2009, 11, 4196.
http://dx.doi.org/10.1021/ol901332e

169

Nucleophilic Opening of Oxabicyclic Ring Systems.

C.S. Schindler, S. Diethelm, E.M. Carreira, Angew. Chem. Int. Ed. 2009, 48, 6296.
http://dx.doi.org/10.1002/anie.200902046

168

Structure determination of slowly Exchanging Conformers in Solution Using High-Resolution NMR, Computational Modeling and DFT-GIAO Chemical Shielding: Application to an Erythronolide A derivative.

D. Muri, C. Corminboeuf, E.M. Carreira, D. Jeannerat, Magn. Reson. Chem. 2009, 47, 909.
http://dx.doi.org/10.1002/mrc.2476

167

Catalytic Decarbonylation of Epoxyaldehydes: Applications to the Preparation of Terminal Epoxides.

B. Morandi, E.M. Carreira, Synlett 2009, 2076.
http://dx.doi.org/10.1055/s-0029-1217562

166

Synthesis and Biophysical Studies on 35-Deoxy Amphotericin B Methyl Ester.

A.M. Szpilman, D.M. Cereghetti, J.M. Manthorpe, N.R. Wurtz, E.M. Carreira, Chem. Eur. J. 2009, 15, 7117.
http://dx.doi.org/10.1002/chem.200900231

165

Synthesis and Investigation of Tryptophan-Amphotericin B Conjugates.

A. Zumbuehl, P. Stano, M. Sohrmann, R. Dietiker, M. Peter, E.M. Carreira, ChemBioChem 2009, 10, 1617.
http://dx.doi.org/10.1002/cbic.200900096

164

β-Glycosidation of Sterically Hindered Alcohols.

A.M. Szpilman, E.M. Carreira, Org. Lett. 2009, 11, 1305.
http://dx.doi.org/10.1021/ol9000735

163

Total Synthesis of a Chlorosulpholipid Cytotoxin Associated with Seafood Poisoning.

C. Nilewski, R.W. Geisser, E.M. Carreira, Nature 2009, 547, 573.
http://dx.doi.org/10.1038/nature07734

162

E.M. Carreira and L. Kværnø, Classics in Stereoselective Synthesis, Wiley: Weinheim, 2009.

161

Total Synthesis of Bafilomycin A1.

F. Kleinbeck, E.M. Carreira, Angew. Chem. Int. Ed. 2009, 48, 578.
http://dx.doi.org/10.1002/anie.200804645   

2008

160

Enantioselective Synthesis of the Core of Banyaside, Suomilide, and Spumigin HKVV.

C.S. Schindler, C.R.J. Stephenson, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 8852.
http://dx.doi.org/10.1002/anie.200803655

159

Enantioselective Synthesis of the Carbocyclic D-Ring Subunit of Massadine.

A. Breder, G.M. Chinigo, A.W. Waltman, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 8514.
http://dx.doi.org/10.1002/anie.200803284

158

Unraveling a Molecular Target of Macrolides.

K.-H. Altmann, E.M. Carreira, Nat. Chem. Biol. 2008, 4, 388.
http://dx.doi.org/10.1038/nchembio0708-388

157

2,6-Diazaspiro[3.3]heptanes: Synthesis and Application in Pd-Catalyzed Aryl Amination Reactions.

J. Burkhard, E.M. Carreira, Org. Lett. 2008, 10, 3525.
http://dx.doi.org/10.1021/ol801293f

156

Catalytic Hydrochlorination of Unactivated Olefins with para-Toluenesulfonyl Chloride.

B. Gaspar, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 5758.
http://dx.doi.org/10.1002/ange.200801760

155

Spirocyclic Oxetanes: Synthesis and Properties.

G. Wuitschik, M. Rogers-Evans, A. Buckl, M. Bernasconi, M. Märki, T. Godel, H. Fischer, B. Wagner, I. Parrilla, F. Schuler, J. Schneider, A. Alker, W.B. Schweizer, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4512.
http://dx.doi.org/10.1002/anie.200800450

154

Synthesis and Biological Studies of 35-Deoxy-Amphotericin B Methyl Ester.

A.M. Szpilman, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4339.
http://dx.doi.org/10.1002/anie.200800590

153

Synthesis of 35-Deoxy Amphotericin B Methylester: A Strategy for Molecular Editing.

A.M. Szpilman, D.M. Cereghetti, N.R. Wurtz, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4335.
http://dx.doi.org/10.1002/anie.200800589

152

J. Waser, E.M. Carreira, Azides by Olefin Hydroazidation Reactions (book chapter), in press.

151

C. Defieber, E.M. Carreira, Modern Arylation Methods, L. Ackerman Ed.
Modern Arylation of Carbonyl Compounds.

150

Chiral Olefins as Steering Ligands in Asymmetric Catalysis.

C. Defieber, H. Grützmacher, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4482.
http://dx.doi.org/10.1002/anie.200703612

149

Synthesis and In Vitro Biological Properties of Novel Cationic Derivatives of Amphotericin B.

V. Paquet, A.A. Volmer, E.M. Carreira, Chem. Eur. J. 2008, 14, 2465.
http://dx.doi.org/10.1002/chem.200701237    

2007

148

Cobalt-Catalyzed Synthesis of Tertiary Azides from α,α-Disubstituted Olefins under Mild Conditions Using Commercially Available Reagents.

B. Gaspar, J. Waser, E.M. Carreira, Synthesis 2007, 3839.
http://dx.doi.org/10.1055/s-2007-1000817

147

Enantioselective Preparation of 1,1-Diarylethanes: Aldehydes as Removable Steering Groups for Asymmetric Synthesis.

T.C. Fessard, S.P. Andrews, H. Motoyoshi, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 9331.
http://dx.doi.org/10.1002/anie.200702995

146

Hydroxyl-Directed Nitrile Oxide Cycloaddition Reactions with Cyclic Allylic Alcohols.

N. Becker, E.M. Carreira, Org. Lett. 2007, 9, 3857.
http://dx.doi.org/10.1021/ol7017032

145

Stereoselective Conjugate Addition Reactions Using In Situ Metallated Terminal Alkynes and the Development of Novel Chiral P,N-Ligands.

S. Fujimori, E.M. Carreira, Bull. Chem. Soc. Jpn. 2007, 80, 1635.
http://dx.doi.org/10.1246/bcsj.80.1635

144

Cu(I)-catalyzed conjugate addition of ethyl propiolate.

S. Fujimori, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 4967.
http://dx.doi.org/10.1002/anie.200701098

143

Enantioselective Reduction of Nitroalkene Mixtures by in situ Equilibration.

C. Czekelius, E.M. Carreira, Org. Process Res. Dev. 2007, 11, 633.
http://dx.doi.org/10.1021/op700029m

142

Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.

M. Knöpfel, J.P. Davies, P.T. Duong, L. Kværnø, E.M. Carreira, M.C. Phillips, Y.A. Ioannou, H. Hauser, Biochim. Biophys. Acta 2007, 1771, 1140.
http://dx.doi.org/10.1016/j.bbalip.2007.05.011

141

Mild Cobalt-Catalyzed Hydrocyanation of Olefins with Tosyl Cyanide.

B. Gaspar, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 4519.
http://dx.doi.org/10.1002/anie.200700575

140

Iridium-Catalyzed Synthesis of Primary Allylic Amines from Allylic Alcohols: Sulfamic Acid as Ammonia Equivalent.

C. Defieber, M.A. Ariger, P. Moriel, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 3139.
http://dx.doi.org/10.1002/anie.200700159

139

Pd-Catalyzed Cleavage of Benzylic Nitro Bonds: New Opportunities for Asymmetric Synthesis.

T.C. Fessard, H. Motoyoshi, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 2078.
http://dx.doi.org/10.1002/anie.200604263

138

Oligothiophene-Linked Bisnaphthopyrans: Sequential and Temperature-Dependent Photochromism.

W.L. Zhao, E.M. Carreira, Chem. Eur. J. 2007, 13, 2671.
http://dx.doi.org/10.1002/chem.200600958

137

A Novel Strategy for Bioconjugation: Synthesis and Preliminary Evaluation with Amphotericin B.

A. Zumbuehl, P. Stano, M. Sohrmann, M. Peter, P. Walde, E.M. Carreira, Org. Biomol. Chem. 2007, 5, 1339.
http://dx.doi.org/10.1039/b701953j    

2006

136

Biologically Active Amphotericin B-calix[4] arene conjugates.

V. Paquet, A. Zumbuehl, E.M. Carreira, Bioconjugate Chem. 2006, 17, 1460.
http://dx.doi.org/10.1021/bc060205i

135

Iridium-Catalyzed Enantioselective Synthesis of Allylic Alcohols: Silanolates as Hydroxide Equivalents.

I. Lyothier, C. Defieber, E.M. Carreira, Angew. Chem. Int. Ed. 2006, 45, 6204.
http://dx.doi.org/10.1002/anie.200602408

134

Oxetanes as Promising Modules in Drug Discovery.

G. Wuitschik, M. Rogers-Evans, K. Muller, H. Fischer, B. Wagner, F. Schuler, L. Polonchuk, E.M. Carreira, Angew. Chem. Int. Ed. 2006, 45, 7736.
http://dx.doi.org/10.1002/anie.200602343

133

Highly Enantioselective Access to Primary Propargylamines: 4-piperidinone as a Convenient Protecting Group.

P. Aschwanden, C.R.J. Stephenson, E.M. Carreira, Org. Lett. 2006, 8, 2437.
http://dx.doi.org/10.1021/ol060876w

132

Hydrazines and Azides via the Metal-Catalyzed Hydrohydrazination and Hydroazidation of olefins.

J. Waser, B. Gaspar, H. Nambu, E.M. Carreira, J. Am. Chem. Soc. 2006, 128, 11693.
http://dx.doi.org/10.1021/ja062355+

131

Amphotericin B: 50 Years of Chemistry and Biochemistry.

D.M. Cereghetti, E.M. Carreira, Synthesis 2006, 914.
http://dx.doi.org/10.1055/s-2006-926368

130

Significant Improvement of Antifungal Activity of Polyene Macrolides by Bisalkylation of the Mycosamine.

V. Paquet, E.M. Carreira, Org. Lett. 2006, 8, 1807.
http://dx.doi.org/10.1021/ol060353o

129

Synthesis and Photochromism of Novel Phenylene-Linked Photochromic Bispyrans.

W. Zhao, E.M. Carreira, Org. Lett. 2006, 8, 99.
http://dx.doi.org/10.1021/ol052587y

128

Synthesis of (+/-)-Strychnofoline via a Highly Convergent Selective Annulation Reaction.

A. Lerchner, E.M. Carreira, Chem. Eur. J. 2006, 12, 8209.
http://dx.doi.org/10.1002/chem.200600957

127

Conformationally Restricted Aza-BODIPY: Highly Fluorescent, Stable Near-Infrared Absorbing Dyes.

W.L. Zhao, E.M. Carreira, Chem. Eur. J. 2006, 12, 7254.
http://dx.doi.org/10.1002/chem.200600527    

2005

126

Reduction of 2,3-Dihydroisoxazoles to beta-Amino Ketones and beta-Amino Alcohols.

P. Aschwanden, L. Kværnø, R.W. Geisser, F. Kleinbeck, E.M. Carreira, Org. Lett. 2005, 25, 5741.
http://dx.doi.org/10.1021/ol052540c

125

Scalable Synthesis of a Mycosamine donor. Overcoming Difficult Reactivity in Allose Systems.

J.M. Manthorpe, A.M. Szpilman, E.M. Carreira, Synthesis 2005, 3380.
http://dx.doi.org/10.1055/s-2005-918474

124

ZnCl2-Mediated Stereoselective Addition of Terminal Alkynes to D-(+)-Mannofuranosyl Nitrones.

D. Topić, P. Aschwanden, R. Fässler, E.M. Carreira, Org. Lett. 2005, 7, 5329.
http://dx.doi.org/10.1021/ol052331s

123

Cobalt-Catalyzed Hydrohydrazination of Dienes and Enynes: Access to Allylic and Propargylic Hydrazides.

J. Waser, J.C. González-Gómez, H. Nambu, P. Huber, E.M. Carreira, Org. Lett. 2005, 7, 4249.
http://dx.doi.org/10.1021/ol0517473

122

Heterocyclic Ring Scaffolds as Small-Molecule Cholesterol Absorption Inhibitors.

T. Ritter, L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, Org. Biomol. Chem. 2005, 19, 3514.
http://dx.doi.org/10.1039/b510100j

121

Catalytic Asymmetric Synthesis with Rh-Diene Complexes: 1,4-Addition of Arylboronic Acids to Unsaturated Esters.

J.-F. Paquin, C.R.J. Stephenson, C. Defieber, E.M. Carreira, Org. Lett. 2005, 7, 3821.
http://dx.doi.org/10.1021/ol051533l

120

Asymmetric Synthesis of 3,3-Diarylpropanals with Chiral Diene-Rhodium Catalysts.

J.-F. Paquin, C. Defieber, C.R.J. Stephenson, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 10850.
http://dx.doi.org/10.1021/ja053270w

119

Catalytic, Enantioselective, Conjugate Alkyne Addition.

T. Knöpfel, P. Zarotti, Y. Takashi, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 9682.
http://dx.doi.org/10.1021/ja052411r

118

Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides.

J. Waser, H. Nambu, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 8294.
http://dx.doi.org/10.1021/ja052164r

117

Synthesis and In Vitro Evaluation of Inhibitors of Intestinal Cholesterol Absorption.

L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, J. Med. Chem. 2005, 48, 6035.
http://dx.doi.org/10.1021/jm050422p

116

Total Synthesis of (-)-Spirotryprostatin B - Synthesis and Related Studies.

C. Marti, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 11505.
http://dx.doi.org/10.1021/ja0518880

115

A Modular Approach to Polyketide Building Blocks: Cycloadditions of Nitrile Oxides and Homoallylic Alcohols.

N. Lohse-Fraefel, E.M. Carreira, Org. Lett. 2005, 7, 2011.
http://dx.doi.org/10.1021/ol0504953

114

Solid Phase Synthesis of Photochromic Spiropyrans.

W. Zhao, E.M. Carreira, Org. Lett. 2005, 7, 1609.
http://dx.doi.org/10.1021/ol050302b

113

Carbohydrate Sulfonyl Chlorides for the Simple, Convenient Access to Glycoconjugates.

L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, Org. Lett. 2005, 7, 1145.
http://dx.doi.org/10.1021/ol0502127

112

Total Synthesis of Erythronolide A via Mg(II)-Mediated Nitrile Oxide Cycloaddition.

D. Muri, N. Lohse, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 4036.
http://dx.doi.org/10.1002/anie.200500172

111

Convenient Transformation of Optically Active Nitroalkanes into Chiral Aldoximes and Nitriles.

C. Czekelius, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 612.
http://dx.doi.org/10.1002/anie.200461879

110

Conformationally Restricted Aza-BODIPY:  A Highly Fluorescent, Stable Near-Infrared Absorbing Dye.

W. Zhao, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 1677.
http://dx.doi.org/10.1002/anie.200461868

 
 
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27.02.2017
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